Spermidine
Bronze· animal data onlyAn autophagy-inducing polyamine with promising animal data and early human hints.
Spermidine is a polyamine, found in foods like wheat germ and aged cheese, that induces autophagy — the cell's recycling process — which is the basis for its longevity interest.
Animal studies show lifespan and cardiovascular benefits, and human observational data link higher dietary spermidine to better outcomes, with small trials hinting at memory effects. But randomised human proof of anti-ageing benefit is still lacking. Food sources are a sensible way to get it.
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Written and reviewed by Mathew Beale, MSc Biotechnology, University of Reading.
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