Vitamin B6 (pyridoxine)

Silver· human data

Also known as: Pyridoxine

Involved in amino-acid metabolism, with some PMS evidence — but excess can harm nerves.

Vitamin B6 is a cofactor in dozens of reactions, especially amino-acid and neurotransmitter metabolism. Correcting a deficiency matters, and there is modest evidence for a benefit in premenstrual symptoms and pregnancy-related nausea.

Unusually for a water-soluble vitamin, chronic high-dose B6 is not harmless: sustained large intakes can cause peripheral nerve damage. Stay near sensible amounts and avoid prolonged megadosing.

Sources

Related supplements

Written and reviewed by Mathew Beale, MSc Biotechnology, University of Reading.

Last reviewed: