Physiologypreliminary · human dataAdded 25 July 2026

In hypertensive Black African adults, ECG-based Cornell voltage product showed moderate association with echocardiographic left ventricular hypertrophy, outperforming other voltage-only criteria, but diagnostic accuracy remains limited.

In hypertensive Black African adults, ECG-based Cornell voltage product showed moderate association with echocardiographic left ventricular hypertrophy, outperforming other voltage-only criteria, but diagnostic accuracy remains limited.

What they did

A cross-sectional subanalysis of 1,125 hypertensive Black African participants in the coArtHA trial compared ECG voltage criteria against echocardiography.

What they found

The Cornell voltage product tracked echocardiographic left ventricular hypertrophy better than other voltage-only criteria, but diagnostic accuracy remained limited.

What it actually shows

Cross-sectional subanalysis of 1,125 hypertensive Black African participants from coArtHA trial; LVH prevalence only 5%; ECG criteria derived from non-African populations; requires external validation and population-specific cut-off refinement.

RCT · Glob Heart

Where it fits

Most ECG thresholds were derived in non-African populations, and hypertrophy prevalence here was only 5%. A reminder that reference ranges are population-specific, not universal.

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