Fact of the day

Thursday, 6 August 2026

Metabolic & GLP-1well supported · human dataDiscovery of the day

Pooling 34 randomised trials in 2461 adults aged 60 and over with type 2 diabetes, every exercise type beat control for HbA1c, but combined aerobic plus resistance training led the field with a 1.05% reduction and ranked first across glycaemic outcomes. Benefits on HbA1c appeared to start at roughly 520 MET-min per week.

Study design
Meta-analysis
Journal
Front Endocrinol (Lausanne)
Evidence
well supported

What it shows: Systematic review and Bayesian network meta-analysis of 34 RCTs (2461 participants, mean age 60+); modality rankings rest on indirect comparisons, the 2-hour glucose evidence was sparse, and the dose-response curves need confirmation in purpose-built trials.Meta-analysis · Front Endocrinol (Lausanne)

The optimal exercise modality and dose for glycemic control in older adults with type 2 diabetes mellitus: a systematic review and network meta-analysis. Front Endocrinol (Lausanne) 2026Read the study →

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