LDL cholesterolLDL-C · 'Bad' cholesterol
Cholesterol carried on the particles most linked to clogged arteries.
LDL cholesterol is the cholesterol carried by low-density lipoproteins (LDL). These particles ferry cholesterol to the body's tissues, and when there are too many of them they can lodge in artery walls and drive the fatty build-up behind heart disease.
It matters because LDL cholesterol is one of the best-evidenced causal factors in cardiovascular disease, and lowering it is among the most reliable ways to reduce that risk. That is why it is often called the 'bad' cholesterol — though the reality is more about particle number than a simple good/bad split.
In practice, LDL is read alongside HDL, triglycerides and ideally ApoB, which counts the atherogenic particles directly and can refine risk when LDL alone looks reassuring.
Put it to use
Related terms
Written and reviewed by Mathew Beale, MSc Biotechnology, University of Reading.
Last reviewed: